PHP3, PHP4 or PHP5: phpMyAdmin widely uses the 'str_replace()' PHP function that was added in PHP 3.0.6, but was buggy up until PHP 3.0.8. Then you should not run this script with PHP3 < 3.0.8.
PHP also needs to be compiled with MySQL support;
If you want to display inline thumbnails of JPEGs, you also need GD2 support in PHP.
MySQL (tested with 3.21.x, 3.22.x, 3.23.x, 4.0.x and 4.1.x);
Note: The implemented MySQL 4.1.x support is experimental!
a web-browser (doh!).